Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 6/20 | 0.73 |
| ▸ | OXTR | P30559 | 5/20 | 0.73 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.44 |
| ▸ | FFAR2 | O15552 | 3/20 | 0.41 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.40 |
| ▸ | GHSR | Q92847 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CCND1 | P24385 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP7 | P09237 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24313533 | 1.00 | AVPR1A (0.73) | AVPR1AOXTRAVPR2FFAR2SLC6A7 | |
| SCHEMBL14492869 | 1.00 | AVPR1A (0.73) | AVPR1AOXTRAVPR2FFAR2SLC6A7 | |
| SCHEMBL29642177 | 1.00 | AVPR1A (0.73) | AVPR1AOXTRAVPR2FFAR2SLC6A7 | |
| SCHEMBL5041466 | 1.00 | AVPR1A (0.73) | AVPR1AOXTRAVPR2FFAR2SLC6A7 | |
| SCHEMBL5041594 | 1.00 | AVPR1A (0.73) | AVPR1AOXTRAVPR2FFAR2SLC6A7 | |
| SCHEMBL4416107 | 0.92 | AVPR1A (0.79) | AVPR1AOXTRAVPR2FFAR2SLC6A7 | |
| SCHEMBL5034150 | 0.92 | AVPR1A (0.79) | AVPR1AOXTRAVPR2FFAR2SLC6A7 | |
| SCHEMBL24313450 | 0.92 | AVPR1A (0.79) | AVPR1AOXTRAVPR2FFAR2SLC6A7 | |
| SCHEMBL29449382 | 0.92 | AVPR1A (0.79) | AVPR1AOXTRAVPR2FFAR2SLC6A7 | |
| SCHEMBL5036670 | 0.92 | AVPR1A (0.79) | AVPR1AOXTRAVPR2FFAR2SLC6A7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3252037-B1 | PROCESS FOR THE PREPARATION OF (3Z,5S)-5-(HYDROXYMETHYL)-1-[(2´-METHYL-1,1´-BIPHENYL-4-YL)CARBONYL)PYRROLIDIN-3-ONE O-METHYLOXIME | ObsEva SA (CH) | 2022-03-09 | — | — | EP | disclosed |