⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3118447 | 1.00 | — | — | |
| SCHEMBL4194222 | 1.00 | — | — | |
| SCHEMBL600016 | 0.86 | KDM4E (0.42) | — | |
| SCHEMBL18583477 | 0.86 | KDM4E (0.42) | — | |
| SCHEMBL6128483 | 0.86 | KDM4E (0.42) | — | |
| SCHEMBL14755201 | 0.86 | KDM4E (0.42) | — | |
| SCHEMBL15542255 | 0.86 | KDM4E (0.42) | — | |
| SCHEMBL18787204 | 0.86 | KDM4E (0.42) | — | |
| SCHEMBL1690354 | 0.84 | SMN1; SMN2 (0.46) | — | |
| SCHEMBL13363702 | 0.84 | SMN1; SMN2 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081739-A1 | METTL3 MODULATORS | ACCENT THERAPEUTICS, INC. (US) | 2022-04-21 | — | — | WO | disclosed |