Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 17/20 | 0.56 |
| ▸ | ABL1 | P00519 | 15/20 | 0.56 |
| ▸ | MTOR | P42345 | 11/20 | 0.56 |
| ▸ | HCK | P08631 | 11/20 | 0.56 |
| ▸ | PIK3CD | O00329 | 11/20 | 0.56 |
| ▸ | PIK3CA | P42336 | 11/20 | 0.56 |
| ▸ | PIK3CB | P42338 | 11/20 | 0.56 |
| ▸ | PIK3CG | P48736 | 11/20 | 0.56 |
| ▸ | PRKDC | P78527 | 10/20 | 0.56 |
| ▸ | EGFR | P00533 | 10/20 | 0.56 |
| ▸ | KDR | P35968 | 9/20 | 0.56 |
| ▸ | EPHB4 | P54760 | 9/20 | 0.56 |
| ▸ | PI4KB | Q9UBF8 | 6/20 | 0.56 |
| ▸ | RICTOR | Q6R327 | 1/20 | 0.54 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.54 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.54 |
| ▸ | MAPKAP1 | Q9BPZ7 | 1/20 | 0.54 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.54 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.53 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7895602 | 0.88 | SRC (0.60) | SRCABL1MTORHCKPIK3CD | |
| SCHEMBL7901661 | 0.84 | SRC (0.66) | SRCABL1MTORHCKPIK3CD | |
| SCHEMBL7902843 | 0.84 | MTOR (0.57) | SRCABL1MTORHCKPIK3CD | |
| SCHEMBL7902699 | 0.84 | SRC (0.56) | SRCABL1MTORHCKPIK3CD | |
| SCHEMBL7901628 | 0.82 | SRC (0.56) | SRCABL1MTORHCKPIK3CD | |
| SCHEMBL7894824 | 0.81 | SRC (0.62) | SRCABL1MTORHCKPIK3CD | |
| SCHEMBL3613904 | 0.79 | SRC (0.67) | SRCABL1MTORHCKPIK3CD | |
| SCHEMBL7894953 | 0.77 | MTOR (0.57) | SRCABL1MTORHCKPIK3CD | |
| SCHEMBL7894970 | 0.76 | ABL1 (0.58) | SRCABL1MTORHCKPIK3CD | |
| SCHEMBL3610515 | 0.72 | SRC (1.00) | SRCABL1MTORHCKPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3153023-B1 | BENZOXAZOLE KINASE INHIBITORS AND METHODS OF USE | TAKEDA PHARMACEUTICALS CO (JP) | 2022-03-16 | — | — | EP | disclosed |