Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 2/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.32 |
| ▸ | MTOR | P42345 | 2/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29904281 | 1.00 | S1PR1 (0.34) | S1PR1PIK3CAPIK3CDPIK3CGMTOR | |
| SCHEMBL24313900 | 0.93 | S1PR1 (0.34) | S1PR1LRRK2CNR2POLBKCNH2 | |
| SCHEMBL29904267 | 0.93 | S1PR1 (0.34) | S1PR1LRRK2CNR2POLBKCNH2 | |
| SCHEMBL29904287 | 0.93 | CNR2 (0.32) | PIK3CAPIK3CDPIK3CGMTORCNR2 | |
| SCHEMBL24313898 | 0.93 | CNR2 (0.32) | PIK3CAPIK3CDPIK3CGMTORCNR2 | |
| SCHEMBL24313905 | 0.93 | S1PR1 (0.34) | S1PR1LRRK2CNR2POLBKCNH2 | |
| SCHEMBL29904271 | 0.93 | S1PR1 (0.34) | S1PR1LRRK2CNR2POLBKCNH2 | |
| SCHEMBL24313969 | 0.93 | S1PR1 (0.34) | S1PR1LRRK2CNR2POLBKCNH2 | |
| SCHEMBL29904283 | 0.93 | S1PR1 (0.34) | S1PR1LRRK2CNR2POLBKCNH2 | |
| SCHEMBL24313915 | 0.92 | S1PR1 (0.33) | S1PR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3585770-B1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2022-03-23 | — | — | EP | disclosed |