SCHEMBL24314408

SCHEMBL24314408

N/C(=N\C(=N/Cc1cccc2oc3ccc(-c4ccc(-c5ccccc5)cc4)cc3c12)c1ccccc1)c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN2B Q13224 6/20 0.37
PLA2G2A P14555 4/20 0.34
PLA2G4A P47712 4/20 0.34
HTR2B P41595 1/20 0.33
PLA2G10 O15496 1/20 0.33
GRIN1 Q05586 3/20 0.32
GRIN2D O15399 1/20 0.32
GRIN3B O60391 1/20 0.32
GRIN2A Q12879 1/20 0.32
GRIN2C Q14957 1/20 0.32
GRIN3A Q8TCU5 1/20 0.32
PRSS1 P07477 1/20 0.32
PRSS2 P07478 1/20 0.32
PRSS3 P35030 1/20 0.32
MMP12 P39900 1/20 0.31
MMP13 P45452 1/20 0.31
TBK1 Q9UHD2 1/20 0.31
AKT1 P31749 1/20 0.31
IDO1 P14902 1/20 0.30
PTPN1 P18031 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24658273 0.99 GRIN2B (0.39) GRIN2BPLA2G2APLA2G4AHTR2BPLA2G10
SCHEMBL24314941 0.93 IDO1 (0.38) GRIN2BPLA2G2APLA2G4AHTR2BPLA2G10
SCHEMBL24315035 0.92 GRIN2B (0.39) GRIN2BHTR2BGRIN1
SCHEMBL25651632 0.92 HTR2B (0.33) GRIN2BPLA2G2APLA2G4AHTR2BPLA2G10
SCHEMBL25652005 0.91 GRIN2B (0.35) GRIN2BPLA2G2APLA2G4AHTR2BIDO1
SCHEMBL24314978 0.90 BACE1 (0.33) GRIN2BHTR2BIDO1
SCHEMBL26284640 0.90 GRIN2B (0.36) GRIN2BPLA2G2APLA2G4AHTR2BPLA2G10
SCHEMBL25639943 0.90
SCHEMBL26066557 0.90
SCHEMBL26035460 0.89 BACE1 (0.33) GRIN2BPLA2G2APLA2G4AHTR2BPLA2G10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3972001-B1 ORGANIC LIGHT EMITTING DEVICE LG CHEMICAL LTD (KR) 2023-06-21 EP disclosed
EP-3972001-A1 ORGANIC LIGHT EMITTING DEVICE LG Chem, Ltd. (KR) 2022-03-23 EP disclosed