Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 20/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | CYP51A1 | Q16850 | 2/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1279572 | 0.81 | CYP3A4 (0.44) | CYP3A4THRBNR1I2LMNAHSP90AA1 | |
| SCHEMBL30611136 | 0.81 | CYP3A4 (0.47) | CYP3A4THRBNR1I2LMNAHSP90AA1 | |
| SCHEMBL21887073 | 0.81 | CYP3A4 (0.47) | CYP3A4THRBNR1I2LMNAHSP90AA1 | |
| Difenoconazole SCHEMBL15932554 | 0.79 | CYP3A4 (0.68) | CYP3A4THRBNR1I2LMNAHSP90AA1 | |
| Difenoconazole SCHEMBL20654517 | 0.79 | CYP3A4 (0.68) | CYP3A4THRBNR1I2LMNAHSP90AA1 | |
| Difenoconazole SCHEMBL22126 | 0.79 | CYP3A4 (0.68) | CYP3A4THRBNR1I2LMNAHSP90AA1 | |
| Difenoconazole SCHEMBL3015472 | 0.79 | CYP3A4 (0.68) | CYP3A4THRBNR1I2LMNAHSP90AA1 | |
| Difenoconazole SCHEMBL15932941 | 0.79 | CYP3A4 (0.68) | CYP3A4THRBNR1I2LMNAHSP90AA1 | |
| Difenoconazole SCHEMBL22125 | 0.79 | CYP3A4 (0.68) | CYP3A4THRBNR1I2LMNAHSP90AA1 | |
| Difenoconazole SCHEMBL29391271 | 0.79 | CYP3A4 (0.68) | CYP3A4THRBNR1I2LMNAHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2547687-B1 | A PROCESS USING GRIGNARD REAGENTS | BASF SE (DE) | 2015-07-01 | — | — | EP | disclosed |
| US-8729272-B2 | Process using grignard reagents | BASF SE (DE) | 2014-05-20 | — | — | US | disclosed |
| EP-2547687-A1 | A PROCESS USING GRIGNARD REAGENTS | BASF SE (DE) | 2013-01-23 | — | — | EP | disclosed |
| US-20130005985-A1 | Process Using Grignard Reagents | BASF SE (DE) | 2013-01-03 | — | — | US | disclosed |
| WO-2011113820-A1 | A PROCESS USING GRIGNARD REAGENTS | BASF SE (DE) | 2011-09-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130005985-A1 | Process Using Grignard Reagents | GTF3C4, GRIA4, GRK4 | CYP3A4 55/4885THRB 587/4885NR1I2 2260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.