Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.50 |
| ▸ | HTR1A | P08908 | 2/20 | 0.50 |
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | HTR2C | P28335 | 2/20 | 0.50 |
| ▸ | HTR2B | P41595 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4009193 | 0.85 | KDM4E (0.46) | MEN1KMT2ACYP3A4KDM4EALDH1A1 | |
| SCHEMBL3555909 | 0.83 | HTR1B (0.55) | MEN1KMT2ACYP3A4KDM4EALDH1A1 | |
| SCHEMBL5229462 | 0.80 | SLC22A6 (0.54) | MEN1KMT2ACYP3A4KDM4ESLC22A6 | |
| SCHEMBL1198964 | 0.77 | SLC22A6 (0.50) | MEN1KMT2ACYP3A4KDM4EALDH1A1 | |
| SCHEMBL25881453 | 0.77 | HTR2A (0.50) | MEN1KMT2ACYP3A4CYP2D6SLC22A6 | |
| SCHEMBL28094105 | 0.77 | SLC22A6 (0.54) | MEN1KMT2ACYP3A4ALDH1A1CYP2D6 | |
| SCHEMBL31744652 | 0.76 | SLC22A6 (0.50) | MEN1KMT2AKDM4EALDH1A1HSD17B10 | |
| SCHEMBL11219841 | 0.74 | SLC22A6 (0.51) | MEN1KMT2ACYP3A4ALDH1A1HSD17B10 | |
| SCHEMBL6989106 | 0.74 | SLC22A6 (0.47) | MEN1KMT2ACYP3A4ALDH1A1CYP2D6 | |
| SCHEMBL31744841 | 0.74 | KMT2A (0.51) | MEN1KMT2ACYP3A4KDM4ESLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022043227-A1 | INJECTABLE FORMULATION | SMALL PHARMA LTD (GB) | 2022-03-03 | — | — | WO | disclosed |
| US-9585884-B2 | Pyrimidinone inhibitors of lipoprotein-associated phospholipase A2 | AUSPEX PHARMACEUTICALS, INC. (US) | 2017-03-07 | — | — | US | disclosed |