Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L11 | O43521 | 1/20 | 0.48 |
| ▸ | BCL2 | P10415 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | CRBN | Q96SW2 | 18/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 13/20 | 0.47 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | IL1B | P01584 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29532776 | 0.88 | CRBN (0.51) | BCL2L11BCL2MCL1CRBNDDB1 | |
| SCHEMBL24315885 | 0.88 | CRBN (0.51) | BCL2L11BCL2MCL1CRBNDDB1 | |
| SCHEMBL29610350 | 0.86 | CRBN (0.49) | BCL2L11BCL2MCL1CRBNDDB1 | |
| SCHEMBL24315959 | 0.86 | CRBN (0.49) | BCL2L11BCL2MCL1CRBNDDB1 | |
| SCHEMBL29610310 | 0.83 | CRBN (0.48) | BCL2L11BCL2MCL1CRBNDDB1 | |
| SCHEMBL24315883 | 0.83 | CRBN (0.48) | BCL2L11BCL2MCL1CRBNDDB1 | |
| SCHEMBL29054873 | 0.83 | CRBN (0.50) | BCL2L11BCL2MCL1CRBNDDB1 | |
| SCHEMBL24329195 | 0.83 | CRBN (0.52) | BCL2L11BCL2MCL1CRBNDDB1 | |
| SCHEMBL26865371 | 0.83 | CRBN (0.51) | BCL2L11BCL2MCL1CRBNDDB1 | |
| SCHEMBL24315843 | 0.82 | CRBN (0.48) | BCL2L11BCL2MCL1CRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081925-A1 | TRICYCLIC LIGANDS FOR DEGRADATION OF IKZF2 OR IKZF4 | C4 THERAPEUTICS, INC. (US) | 2022-04-21 | — | — | WO | disclosed |