SCHEMBL2431715

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2431720	1.00	AXL (0.38)	AXLROCK1METMERTKKDR
	SCHEMBL2433375	0.93	AXL (0.40)	AXLROCK1METMERTKKDR
	SCHEMBL2433376	0.93	AXL (0.40)	AXLROCK1METMERTKKDR
	SCHEMBL2431360	0.89	NPC1 (0.39)	ROCK1KDM4ERAB9AKMT2ANPC1
	SCHEMBL2431361	0.89	NPC1 (0.39)	ROCK1KDM4ERAB9AKMT2ANPC1
	SCHEMBL2431367	0.86	S1PR1 (0.37)	CYP2E1S1PR1P2RX3
	SCHEMBL2431370	0.86	S1PR1 (0.37)	CYP2E1S1PR1P2RX3
	SCHEMBL2429269	0.86	ROCK1 (0.39)	AXLROCK1METMERTKKDR
	SCHEMBL2429273	0.86	ROCK1 (0.39)	AXLROCK1METMERTKKDR
	SCHEMBL2429921	0.85	GRM4 (0.41)	KDRKDM4ERAB9ANPC1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.