Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP2A13 | Q16696 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26620040 | 0.87 | PTGDR2 (0.47) | PTGDR2CYP2D6CYP3A4TSHRNPC1 | |
| SCHEMBL24317328 | 0.87 | PTGDR2 (0.44) | PTGDR2CYP2D6CYP3A4TSHRNPC1 | |
| SCHEMBL26620037 | 0.85 | PTGDR2 (0.43) | PTGDR2CYP2D6CYP3A4TSHRNPC1 | |
| SCHEMBL24315786 | 0.85 | CYP2D6 (0.44) | PTGDR2CYP2D6CYP3A4TSHRNPC1 | |
| SCHEMBL26620044 | 0.83 | CYP2D6 (0.46) | PTGDR2CYP2D6CYP3A4TSHRNPC1 | |
| SCHEMBL27010239 | 0.83 | PTGDR2 (0.42) | PTGDR2CYP2D6CYP3A4TSHRNPC1 | |
| SCHEMBL26620334 | 0.82 | PTGDR2 (0.48) | PTGDR2CYP2D6CYP3A4TSHRNPC1 | |
| SCHEMBL24316060 | 0.81 | PTGDR2 (0.48) | PTGDR2CYP3A4TSHRNPC1ALDH1A1 | |
| SCHEMBL26620324 | 0.81 | PTGDR2 (0.45) | PTGDR2CYP2D6CYP3A4TSHRNPC1 | |
| SCHEMBL24315785 | 0.80 | PTGDR2 (0.42) | PTGDR2CYP2D6CYP3A4TSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081927-A1 | TRICYCLIC COMPOUNDS TO DEGRADE NEOSUBSTRATES FOR MEDICAL THERAPY | C4 THERAPEUTICS, INC. (US) | 2022-04-21 | — | — | WO | disclosed |