Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 3/20 | 0.42 |
| ▸ | PRCP | P42785 | 3/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31569336 | 0.78 | RECQL (0.39) | CXCR4PRCPCYP2D6RECQLKDM4E | |
| SCHEMBL1011519 | 0.78 | RECQL (0.39) | CXCR4PRCPCYP2D6RECQLKDM4E | |
| SCHEMBL14159530 | 0.75 | HTR2A (0.33) | — | |
| SCHEMBL31569143 | 0.74 | PRCP (0.39) | CXCR4PRCPSLC22A1CYP2D6OPRM1 | |
| SCHEMBL24019184 | 0.74 | PRCP (0.58) | CXCR4PRCPCYP2D6RECQLFNTA | |
| SCHEMBL27420117 | 0.74 | FNTA (0.38) | CXCR4PRCPCYP2D6RECQLFNTA | |
| SCHEMBL12483568 | 0.74 | BCHE (0.52) | KDM4EGAAMAPTHTT | |
| Hydrochloric Acid SCHEMBL4794231 | 0.73 | HTR2A (0.35) | — | |
| SCHEMBL1011090 | 0.73 | PRCP (0.68) | PRCPSLC22A1OPRM1KDM4EGAA | |
| SCHEMBL29768301 | 0.73 | PRCP (0.68) | PRCPSLC22A1OPRM1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081927-A1 | TRICYCLIC COMPOUNDS TO DEGRADE NEOSUBSTRATES FOR MEDICAL THERAPY | C4 THERAPEUTICS, INC. (US) | 2022-04-21 | — | — | WO | disclosed |