SCHEMBL24318101 — predicted protein targets

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	TSHR	P16473	1/20	0.60

▸	GAA	P10253	1/20	0.58

▸	FABP7	O15540	4/20	0.58

▸	PPARG	P37231	4/20	0.57

▸	MEN1	O00255	1/20	0.57

▸	CYP1A2	P05177	1/20	0.57

▸	CYP2D6	P10635	1/20	0.57

▸	CYP2C19	P33261	1/20	0.57

▸	KMT2A	Q03164	1/20	0.57

▸	FABP5	Q01469	3/20	0.57

▸	POLB	P06746	2/20	0.54

▸	TP53	P04637	1/20	0.52

▸	KDM4E	B2RXH2	1/20	0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL17366557	0.96	GAA (0.63)	TSHRGAAFABP7PPARGMEN1
SCHEMBL18462855	0.96	GAA (0.63)	TSHRGAAFABP7PPARGMEN1
SCHEMBL18418086	0.96	GAA (0.63)	TSHRGAAFABP7PPARGMEN1
SCHEMBL5122894	0.93	TSHR (0.60)	TSHRGAAFABP7PPARGMEN1
SCHEMBL14276798	0.93	TSHR (0.60)	TSHRGAAFABP7PPARGMEN1
SCHEMBL26036694	0.91	GAA (0.71)	TSHRGAAFABP7PPARGMEN1
SCHEMBL18828500	0.88	MEN1 (0.57)	TSHRGAAFABP7PPARGMEN1
SCHEMBL6425222	0.86	TSHR (0.54)	TSHRGAAFABP7PPARGMEN1
SCHEMBL6425221	0.86	TSHR (0.54)	TSHRGAAFABP7PPARGMEN1
SCHEMBL15768992	0.85	TSHR (0.53)	TSHRGAAFABP7PPARGMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2022041462-A1	SYNTHESIS METHOD FOR CYCLOPROPANE COMPOUND	凯莱英生命科学技术(天津)有限公司	2022-03-03	—	—	WO	disclosed