Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRB | P23467 | 20/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL500826 | 0.91 | PTPRB (1.00) | PTPRB | |
| SCHEMBL30858801 | 0.91 | PTPRB (1.00) | PTPRB | |
| SCHEMBL500123 | 0.91 | PTPRB (1.00) | PTPRB | |
| SCHEMBL500827 | 0.91 | PTPRB (1.00) | PTPRB | |
| SCHEMBL500124 | 0.91 | PTPRB (1.00) | PTPRB | |
| SCHEMBL499660 | 0.91 | PTPRB (1.00) | PTPRB | |
| SCHEMBL30055842 | 0.91 | PTPRB (1.00) | PTPRB | |
| SCHEMBL499661 | 0.91 | PTPRB (1.00) | PTPRB | |
| SCHEMBL500469 | 0.90 | PTPRB (1.00) | PTPRB | |
| SCHEMBL500468 | 0.90 | PTPRB (1.00) | PTPRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3977994-A1 | ACTIVATORS OF TIE-2 FOR USE IN TREATING INTRAOCULAR PRESSURE | Aerpio Pharmaceuticals, Inc. (US) | 2022-04-06 | — | — | EP | disclosed |