Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 20/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2433334 | 1.00 | PTGER4 (0.63) | PTGER4 | |
| SCHEMBL2295580 | 0.94 | PTGER4 (0.70) | PTGER4 | |
| SCHEMBL2429354 | 0.91 | PTGER4 (0.62) | PTGER4 | |
| SCHEMBL2430703 | 0.91 | PTGER4 (0.62) | PTGER4 | |
| SCHEMBL1590115 | 0.89 | PTGER4 (0.62) | PTGER4 | |
| SCHEMBL1590613 | 0.89 | PTGER4 (0.62) | PTGER4 | |
| SCHEMBL1590185 | 0.88 | PTGER4 (0.62) | PTGER4 | |
| SCHEMBL2297173 | 0.88 | PTGER4 (0.60) | PTGER4 | |
| SCHEMBL2431779 | 0.87 | PTGER4 (0.44) | PTGER4 | |
| SCHEMBL2429198 | 0.86 | PTGER4 (0.73) | PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8026270-B2 | Benzo [F] isoindoles as EP4 receptor agonists | GLAXO GROUP LIMITED (GB) | 2011-09-27 | — | — | US | disclosed |