Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | NPY1R | P25929 | 1/20 | 0.47 |
| ▸ | NPY2R | P49146 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17285638 | 1.00 | KMT2A (0.56) | KMT2AMEN1SLC18A3TSHRNPSR1 | |
| SCHEMBL24319647 | 1.00 | KMT2A (0.56) | KMT2AMEN1SLC18A3TSHRNPSR1 | |
| SCHEMBL18159897 | 0.84 | KMT2A (0.53) | KMT2AMEN1SLC18A3TSHRNPSR1 | |
| SCHEMBL23155886 | 0.83 | MAPT (0.59) | KMT2AMEN1TSHRNPSR1USP2 | |
| SCHEMBL13014522 | 0.83 | MAPT (0.59) | KMT2AMEN1TSHRNPSR1USP2 | |
| SCHEMBL8276581 | 0.83 | SLC18A3 (0.56) | KMT2AMEN1SLC18A3TSHRUSP2 | |
| SCHEMBL2801641 | 0.82 | KMT2A (0.52) | KMT2AMEN1SLC18A3TSHRUSP2 | |
| SCHEMBL26816771 | 0.82 | SLC18A3 (0.54) | KMT2AMEN1SLC18A3TSHRNPSR1 | |
| SCHEMBL7278149 | 0.82 | KMT2A (0.46) | KMT2AMEN1SLC18A3TSHRNPSR1 | |
| SCHEMBL24491489 | 0.80 | KMT2A (0.53) | KMT2AMEN1TSHRNPSR1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022047145-A1 | RAPIDLY ACCELERATING FIBROSARCOMA PROTEIN DEGRADING COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2022-03-03 | — | — | WO | disclosed |