Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 6/20 | 0.54 |
| ▸ | CSNK2B | P67870 | 6/20 | 0.54 |
| ▸ | CSNK2A1 | P68400 | 6/20 | 0.54 |
| ▸ | PIM1 | P11309 | 14/20 | 0.52 |
| ▸ | SGK1 | O00141 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2425919 | 0.87 | PIM1 (0.59) | CSNK2A2CSNK2BCSNK2A1PIM1 | |
| SCHEMBL1819537 | 0.71 | CSNK2A2 (0.83) | CSNK2A2CSNK2BCSNK2A1PIM1 | |
| SCHEMBL1759422 | 0.71 | CSNK2A2 (1.00) | CSNK2A2CSNK2BCSNK2A1PIM1 | |
| SCHEMBL1817935 | 0.69 | PIM1 (0.65) | CSNK2A2CSNK2BCSNK2A1PIM1SGK1 | |
| SCHEMBL1760566 | 0.68 | CSNK2A1 (1.00) | CSNK2A2CSNK2BCSNK2A1PIM1 | |
| SCHEMBL1814527 | 0.68 | PIM1 (1.00) | CSNK2A2CSNK2BCSNK2A1PIM1 | |
| SCHEMBL1816869 | 0.64 | CSNK2A1 (0.53) | CSNK2A2CSNK2BCSNK2A1PIM1SGK1 | |
| SCHEMBL1759675 | 0.63 | CSNK2A1 (1.00) | CSNK2A2CSNK2BCSNK2A1PIM1 | |
| SCHEMBL1813051 | 0.63 | CSNK2A1 (0.51) | CSNK2A2CSNK2BCSNK2A1PIM1SGK1 | |
| SCHEMBL10322725 | 0.61 | PIM1 (0.81) | CSNK2A2CSNK2BCSNK2A1PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2366695-A1 | A compound, a process for its preparation, a pharmaceutical composition, use of a compound, a method for modulating or regulating serine/threonine kinases and a serine/threonine kinases modulating agent | SELVITA S.A. (PL) | 2011-09-21 | — | — | EP | claimed |