Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 17/20 | 0.56 |
| ▸ | CCND1 | P24385 | 15/20 | 0.56 |
| ▸ | CDK6 | Q00534 | 8/20 | 0.56 |
| ▸ | CDK2 | P24941 | 3/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24322134 | 0.89 | CCND1 (0.55) | CDK4CCND1CDK6CDK2CCNE1 | |
| SCHEMBL29514987 | 0.89 | CCND1 (0.55) | CDK4CCND1CDK6CDK2CCNE1 | |
| SCHEMBL29515067 | 0.75 | CDK4 (0.84) | CDK4CCND1CDK6CDK2CDK1 | |
| SCHEMBL29515058 | 0.75 | CCND1 (0.68) | CDK4CCND1CDK6CDK2CCNE1 | |
| SCHEMBL25285170 | 0.75 | CCND1 (0.68) | CDK4CCND1CDK6CDK2CCNE1 | |
| SCHEMBL24322323 | 0.74 | CCND1 (1.00) | CDK4CCND1CDK6CDK2CDK1 | |
| SCHEMBL25243806 | 0.74 | CCND1 (1.00) | CDK4CCND1CDK6CDK2CDK1 | |
| SCHEMBL25285207 | 0.74 | CCND1 (1.00) | CDK4CCND1CDK6CDK2CCNE1 | |
| SCHEMBL25289547 | 0.74 | CCND1 (0.79) | CDK4CCND1CDK6CDK2CCNE1 | |
| SCHEMBL29515116 | 0.74 | CCND1 (0.79) | CDK4CCND1CDK6CDK2CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022061273-A1 | CDK INHIBITORS AND THEIR USE AS PHARMACEUTICALS | PRELUDE THERAPEUTICS, INCORPORATED (US) | 2022-03-24 | — | — | WO | disclosed |