Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 14/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24321687 | 0.88 | HSP90AA1 (0.40) | HSP90AA1HSP90AB1KDM4EALOX15TDP1 | |
| SCHEMBL500957 | 0.88 | BRD4 (0.44) | BRD4HSP90AA1HSP90AB1 | |
| SCHEMBL24321262 | 0.87 | HSP90AA1 (0.46) | HSP90AA1HSP90AB1KDM4EALOX15TDP1 | |
| SCHEMBL24322223 | 0.86 | BRD4 (0.43) | BRD4HSP90AA1HSP90AB1KDM4ETDP1 | |
| SCHEMBL501355 | 0.86 | BRD4 (0.45) | BRD4HSP90AA1HSP90AB1 | |
| SCHEMBL24321187 | 0.85 | BRD4 (0.44) | BRD4HSP90AA1HSP90AB1ACKR3 | |
| SCHEMBL24321360 | 0.83 | BRD4 (0.43) | BRD4HSP90AA1HSP90AB1KDM4ETDP1 | |
| SCHEMBL24322266 | 0.83 | HSP90AA1 (0.43) | BRD4HSP90AA1HSP90AB1 | |
| SCHEMBL15648822 | 0.83 | BRD4 (0.46) | BRD4HSP90AA1HSP90AB1 | |
| SCHEMBL501486 | 0.82 | HSP90AA1 (0.50) | HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078414-A1 | METHODS AND COMPOSITIONS FOR TARGETED PROTEIN DEGRADATION | RANOK THERAPEUTICS (HANGZHOU) CO. LTD. (CN) | 2022-04-21 | — | — | WO | disclosed |