SCHEMBL2432243

SCHEMBL2432243

CC(C)(NC(N)=O)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.55
KMT2A Q03164 1/20 0.55
SSTR4 P31391 1/20 0.50
HDAC3 O15379 2/20 0.47
HDAC1 Q13547 2/20 0.47
HDAC2 Q92769 2/20 0.47
HDAC6 Q9UBN7 2/20 0.47
HDAC4 P56524 1/20 0.47
HDAC7 Q8WUI4 1/20 0.47
HDAC10 Q969S8 1/20 0.47
HDAC11 Q96DB2 1/20 0.47
HDAC8 Q9BY41 1/20 0.47
HDAC9 Q9UKV0 1/20 0.47
HDAC5 Q9UQL6 1/20 0.47
F7 P08709 1/20 0.46
KCNN4 O15554 1/20 0.44
CYP2C19 P33261 1/20 0.44
HIF1A Q16665 1/20 0.44
CYP1A2 P05177 2/20 0.44
CYP3A4 P08684 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24834141 0.83 SSTR4 (0.50) MAPTKMT2ASSTR4HDAC3HDAC1
SCHEMBL28376940 0.83 MAPT (0.55) MAPTKMT2ASSTR4HDAC3HDAC1
SCHEMBL8384935 0.83 SSTR4 (0.53) MAPTKMT2ASSTR4HDAC3HDAC1
SCHEMBL935057 0.83 SSTR4 (0.53) MAPTKMT2ASSTR4HDAC3HDAC1
SCHEMBL9971091 0.82 NPC1 (0.46) MAPTHDAC1HDAC6GAA
SCHEMBL27279094 0.81 SSTR4 (0.51) MAPTKMT2ASSTR4HDAC3HDAC1
SCHEMBL2283304 0.81 SSTR4 (0.51) MAPTKMT2ASSTR4HDAC3HDAC1
Hydrochloric Acid SCHEMBL4323383 0.81 SSTR4 (0.51) MAPTKMT2ASSTR4HDAC3HDAC1
SCHEMBL10928791 0.80 SSTR4 (0.47) MAPTKMT2ASSTR4HDAC3HDAC1
SCHEMBL11136765 0.80 POLB (0.49) MAPTKMT2ASSTR4CYP2C19CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0182166-B1 PROCESS FOR PREPARING PHENYLISOPROPYLUREA COMPOUNDS AMERICAN CYANAMID COMPANY (US) 1989-05-31 EP claimed
EP-0182166-A2 Process for preparing phenylisopropylurea compounds AMERICAN CYANAMID COMPANY (US) 1986-05-28 EP claimed
US-4578513-A Process for preparing phenylisopropylurea compounds AMERICAN CYANAMID COMPANY (US) 1986-03-25 US claimed
US-4039577-A Process for preparing phenylisopropylurea derivatives SHOWA DENKO K.K. (JA) 1977-08-02 US claimed
CN-120035584-A Substituted N-phenyluracils and salts thereof and their use as herbicidal agents 拜耳公司 2025-05-23 CN disclosed
CN-114531883-B Film and method for producing same 日东电工株式会社 2024-07-09 CN disclosed
US-20230303549-A1 SUBSTITUTED HETEROARYLOXYPYRIDINES, THE SALTS THEREOF AND THEIR USE AS HERBICIDAL AGENTS BAYER AKTIENGESELLSCHAFT (DE) 2023-09-28 US disclosed
EP-3795564-A1 COMPOUND, CURABLE AGENT COMPOSITION, RESIN COMPOSITION, COATING COMPOSITION AND RESIN CURED PRODUCT Asahi Kasei Kabushiki Kaisha (JP) 2021-03-24 EP disclosed
US-9526241-B2 Dispersants for agricultural applications AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) 2016-12-27 US disclosed
US-9526241-B2 Dispersants for agricultural applications AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) 2016-12-27 US disclosed
US-9232786-B2 Dispersants for agricultural applications AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) 2016-01-12 US disclosed
US-9232786-B2 Dispersants for agricultural applications AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) 2016-01-12 US disclosed
US-4578513-A Process for preparing phenylisopropylurea compounds AMERICAN CYANAMID COMPANY (US) 1986-03-25 US disclosed
US-4143061-A 3-(α,α-Dimethylbenzyl)urea compounds, compositions, and their use as herbicides SHOWA DENKO KABUSHIKI KAISHA (JP) 1979-03-06 US disclosed
US-4143061-A 3-(α,α-Dimethylbenzyl)urea compounds, compositions, and their use as herbicides SHOWA DENKO KABUSHIKI KAISHA (JP) 1979-03-06 US disclosed
US-4039577-A Process for preparing phenylisopropylurea derivatives SHOWA DENKO K.K. (JA) 1977-08-02 US disclosed
US-4039577-A Process for preparing phenylisopropylurea derivatives SHOWA DENKO K.K. (JA) 1977-08-02 US disclosed
US-4039577-A Process for preparing phenylisopropylurea derivatives SHOWA DENKO K.K. (JA) 1977-08-02 US disclosed
US-3972909-A α,α-Dimethylbenzylureas and use as herbicides Shova Denko Kabushiki Kaisha (JA) 1976-08-03 US disclosed
US-3972909-A α,α-Dimethylbenzylureas and use as herbicides Shova Denko Kabushiki Kaisha (JA) 1976-08-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230303549-A1 SUBSTITUTED HETEROARYLOXYPYRIDINES, THE SALTS THEREOF AND THEIR USE AS HERBICIDAL AGENTS DDT, AGPS, GMDS MAPT 4307/4885KMT2A 2025/4885SSTR4 1861/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.