⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1908494 | 1.00 | — | — | |
| SCHEMBL55 | 1.00 | — | — | |
| Charcoal, Activated SCHEMBL9804777 | 0.93 | — | — | |
| SCHEMBL15841463 | 0.93 | — | — | |
| Fluoride SCHEMBL424665 | 0.93 | — | — | |
| SCHEMBL3200175 | 0.93 | — | — | |
| SCHEMBL10617974 | 0.93 | — | — | |
| Fluoride SCHEMBL9374351 | 0.93 | — | — | |
| SCHEMBL7071040 | 0.93 | — | — | |
| Ethylene SCHEMBL905584 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3919496-A1 | POLYCYCLIC COMPOUND INHIBITING MNK1 AND MNK2 | Novostar Pharmaceuticals, Ltd. (CN) | 2021-12-08 | — | — | EP | claimed |
| CN-113330014-A | Polycyclic compounds that inhibit MNK1 and MNK2 | 诺沃斯达药业(上海)有限公司 | 2021-08-31 | — | — | CN | claimed |
| WO-2020155842-A1 | POLYCYCLIC COMPOUND INHIBITING MNK1 AND MNK2 | 诺沃斯达药业有限公司 | 2020-08-06 | — | — | WO | claimed |
| CN-111484494-A | Polycyclic compounds that inhibit MNK1 and MNK2 | 诺沃斯达药业有限公司 | 2020-08-04 | — | — | CN | claimed |
| US-7030283-B2 | Process for producing 1,1-difluorovinyl cycloaliphatic compounds | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2006-04-18 | — | — | US | claimed |
| US-20050165260-A1 | Process for producing 1,1-difluorovinyl cycloaliphatic compounds | VERSUM MATERIALS US, LLC | 2005-07-28 | — | — | US | claimed |
| EP-1557404-A1 | Process for producing 1,1-Difluorovinyl cycloaliphatic compounds | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2005-07-27 | — | — | EP | claimed |
| US-6864397-B2 | Difluoromethyl ether derivative and process for producing the same | CHISSO CORPORATION (JP) | 2005-03-08 | — | — | US | claimed |
| US-20040016906-A1 | Difluoromethyl ether derivative and process for producing the same | JNC CORPORATION (JP) | 2004-01-29 | — | — | US | claimed |
| US-20040004207-A1 | Difluoromethyl ether derivative and process for producing the same | JNC CORPORATION (JP) | 2004-01-08 | — | — | US | claimed |
| US-20020120168-A1 | Difluoromethyl ether derivative and process for producing the same | JNC PETROCHEMICAL CORPORATION (JP) | 2002-08-29 | — | — | US | claimed |
| EP-1182186-A2 | Difluoromethyl ether derivative and process for producing the same | CHISSO CORPORATION (JP) | 2002-02-27 | — | — | EP | claimed |
| CN-113330014-B | Polycyclic compounds that inhibit MNK1 and MNK2 | 诺沃斯达药业(上海)有限公司 | 2023-08-08 | — | — | CN | disclosed |
| CN-111484494-B | Polycyclic compounds that inhibit MNK1 and MNK2 | 诺沃斯达药业(上海)有限公司 | 2022-09-13 | — | — | CN | disclosed |
| CN-111801608-B | Plastic optical fiber and plastic optical fiber cord | 东丽株式会社 | 2022-08-12 | — | — | CN | disclosed |
| CN-110382603-B | Crosslinked poly (1, 1-difluoroethylene) resin foam sheet and process for producing the same | 积水化学工业株式会社 | 2022-05-24 | — | — | CN | disclosed |
| EP-0750028-B1 | Alkenylcyclohexane derivatives, liquid crystal composition and liquid crystal display element | CHISSO CORP (JP) | 2001-04-18 | — | — | EP | disclosed |
| US-5776367-A | Alkenylcyclohexane derivatives, liquid crystal composition and liquid crystal display element | CHISSO CORPORATION (JP) | 1998-07-07 | — | — | US | disclosed |
| EP-0750028-A2 | Alkenylcyclohexane derivatives, liquid crystal composition and liquid crystal display element | Chisso Corporation (JP) | 1996-12-27 | — | — | EP | disclosed |
| US-4950666-A | INSECTS, ACARIDS, AND NEMATODES | FMC CORPORATION (US) | 1990-08-21 | — | — | US | disclosed |