SCHEMBL24323804

SCHEMBL24323804

N=C(N)c1cccc(CN2CC[C@H](NCC(N)=O)C2=O)c1

nearest known ligand 0.61

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.61
PLG P00747 1/20 0.60
PROC P04070 1/20 0.60
F2 P00734 7/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24322945 0.93 F10 (0.63) F10PLGPROCF2
SCHEMBL24322550 0.89 F10 (0.59) F10PLGPROCF2
SCHEMBL24322558 0.88 F10 (0.62) F10PLGPROCF2
SCHEMBL24324315 0.85 F10 (0.67) F10PLGPROCF2
SCHEMBL24322949 0.85 F10 (0.67) F10PLGPROCF2
SCHEMBL7413859 0.81 F10 (0.56) F10PLGPROCF2
SCHEMBL24323873 0.80 F10 (0.58) F10PLGPROCF2
SCHEMBL24322934 0.80 F10 (0.58) F10PLGPROCF2
SCHEMBL7425743 0.78 F10 (0.56) F10PLGPROCF2
SCHEMBL7421559 0.78 F10 (0.56) F10PLGPROCF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220122691-A1 HtrA Inhibitors and CagA Inhibitors and Use Thereof Psomagen Inc. (US) 2022-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220122691-A1 HtrA Inhibitors and CagA Inhibitors and Use Thereof HTRA1, GIPR, HPN F10 1781/4885PLG 1769/4885PROC 3215/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.