⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9204921 | 0.80 | — | — | |
| SCHEMBL2307497 | 0.76 | — | — | |
| SCHEMBL282247 | 0.70 | — | — | |
| SCHEMBL1569445 | 0.69 | — | — | |
| SCHEMBL13541827 | 0.69 | GFER (0.35) | — | |
| SCHEMBL10025529 | 0.69 | GFER (0.35) | — | |
| SCHEMBL20163169 | 0.68 | — | — | |
| SCHEMBL16388347 | 0.68 | — | — | |
| SCHEMBL6999054 | 0.68 | — | — | |
| SCHEMBL5160070 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9695154-B2 | Heteroaryl inhibitors of sumo activating enzyme | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2017-07-04 | — | — | US | disclosed |
| US-9695154-B2 | Heteroaryl inhibitors of sumo activating enzyme | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2017-07-04 | — | — | US | disclosed |
| US-20160355504-A1 | HETEROARYL INHIBITORS OF SUMO ACTIVATING ENZYME | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2016-12-08 | — | — | US | disclosed |
| US-20160355504-A1 | HETEROARYL INHIBITORS OF SUMO ACTIVATING ENZYME | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2016-12-08 | — | — | US | disclosed |
| US-8673948-B2 | Chemical compounds | GlaxoSmithKline, LLC (US) | 2014-03-18 | — | — | US | disclosed |
| US-8673948-B2 | Chemical compounds | GlaxoSmithKline, LLC (US) | 2014-03-18 | — | — | US | disclosed |
| US-8673948-B2 | Chemical compounds | GlaxoSmithKline, LLC (US) | 2014-03-18 | — | — | US | disclosed |
| EP-2079466-B1 | SUBSTITUTED INDOLE COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2014-01-15 | — | — | EP | disclosed |
| EP-2079466-B1 | SUBSTITUTED INDOLE COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2014-01-15 | — | — | EP | disclosed |
| CN-101663303-B | Heteroaromatic compounds, the preparation method and the use thereof | SUN PIAOYANG | 2012-06-27 | — | — | CN | disclosed |
| US-6956040-B2 | Oxazolidinone piperazinyl derivatives as potential antimicrobials | RANBAXY LABORATORIES LIMITED (IN) | 2005-10-18 | — | — | US | disclosed |
| US-20040254162-A1 | Oxazolidinone derivatives as antimicrobials | RANBAXY LABORATORIES LIMITED (IN) | 2004-12-16 | — | — | US | disclosed |
| US-6734307-B2 | USE AGAINST MULTIPLY RESISTANT GRAM POSITIVE PATHOGENS; HAVE A DIAZINE MOIETY ATTACHED TO THE PHENYLOXAZOLIDINONE WHICH IS FURTHER SUBSTITUTED BY HETEROCYCLIC, ARYL, SUBSTITUTED ARYL, HETEROAROAMATIC RING | RANBAXY LABORATORIES LIMITED (IN) | 2004-05-11 | — | — | US | disclosed |
| EP-1409465-A2 | OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS | RANBAXY LABORATORIES, LTD. (IN) | 2004-04-21 | — | — | EP | disclosed |
| CN-1447808-A | Oxazolidinone derivatives as anticrobials | RANBAXY LAB LTD (IN) | 2003-10-08 | — | — | CN | disclosed |
| US-20030119817-A1 | Oxazolidinone derivatives as potential antimicrobials | MEHTA ANITA (IN) | 2003-06-26 | — | — | US | disclosed |
| EP-1303511-A1 | OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS | RANBAXY LABORATORIES, LTD. (IN) | 2003-04-23 | — | — | EP | disclosed |
| WO-2003007870-A2 | OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS | RANBAXY LABORATORIES LIMITED (IN) | 2003-01-30 | — | — | WO | disclosed |
| US-20020103186-A1 | Oxazolidinone derivatives as antimicrobials disease | RANBAXY LABORATORIES LIMITED (IN) | 2002-08-01 | — | — | US | disclosed |
| WO-2002006278-A1 | OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS | RANBAXY LABORATORIES LIMITED (IN) | 2002-01-24 | — | — | WO | disclosed |