Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 20/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29446381 | 0.91 | PLK1 (1.00) | PLK1 | |
| SCHEMBL24324069 | 0.91 | PLK1 (1.00) | PLK1 | |
| SCHEMBL29446445 | 0.89 | PLK1 (0.88) | PLK1 | |
| SCHEMBL26852119 | 0.87 | PLK1 (1.00) | PLK1 | |
| SCHEMBL29446355 | 0.87 | PLK1 (1.00) | PLK1 | |
| SCHEMBL24324356 | 0.87 | PLK1 (1.00) | PLK1 | |
| SCHEMBL24324427 | 0.87 | PLK1 (1.00) | PLK1 | |
| SCHEMBL29446434 | 0.87 | PLK1 (1.00) | PLK1 | |
| SCHEMBL29446453 | 0.85 | PLK1 (1.00) | PLK1 | |
| SCHEMBL29446370 | 0.85 | PLK1 (1.00) | PLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022067100-A2 | PLK1 POLO BOX DOMAIN INHIBITOR AND METHOD OF TREATING CANCER | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2022-03-31 | — | — | WO | disclosed |