Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 3/20 | 0.32 |
| ▸ | IL1RN | P18510 | 1/20 | 0.31 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.31 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28753978 | 0.91 | KDM4E (0.35) | HTR2CHTR2AHTR2BIL1RNERAP2 | |
| SCHEMBL30509287 | 0.79 | HTR2C (0.40) | HTR2CHTR2AHTR2BIL1RNERAP2 | |
| SCHEMBL13249026 | 0.79 | HTR2C (0.40) | HTR2CHTR2AHTR2BIL1RNERAP2 | |
| SCHEMBL6674584 | 0.76 | RXFP1 (0.51) | — | |
| SCHEMBL13105773 | 0.74 | NISCH (0.44) | HTR2CHTR2AHTR2BNISCHKDM4E | |
| SCHEMBL10463782 | 0.74 | HTR2C (0.40) | HTR2CHTR2AHTR2BIL1RNERAP2 | |
| SCHEMBL13249030 | 0.73 | DRD4 (0.35) | HTR2CNISCHIL1RNERAP2ERAP1 | |
| SCHEMBL21646755 | 0.72 | USP2 (0.45) | KDM4E | |
| SCHEMBL2952459 | 0.72 | RXFP1 (0.51) | — | |
| SCHEMBL13585896 | 0.70 | HTR2C (0.40) | HTR2CHTR2AHTR2BIL1RNERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022063106-A1 | INDOLINE COMPOUNDS AND DERIVATIVES AS EGFR INHIBITORS | BEIGENE, LTD. (KY) | 2022-03-31 | — | — | WO | disclosed |