Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 13/20 | 0.56 |
| ▸ | ITGA4 | P13612 | 13/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7269962 | 1.00 | ITGB1 (0.56) | ITGB1ITGA4MEN1KMT2AKDM1A | |
| SCHEMBL2432788 | 0.89 | ITGB1 (0.71) | ITGB1ITGA4MEN1KMT2AKDM1A | |
| SCHEMBL2430237 | 0.89 | ITGB1 (0.71) | ITGB1ITGA4MEN1KMT2AKDM1A | |
| SCHEMBL2432751 | 0.83 | ITGB1 (0.80) | ITGB1ITGA4 | |
| SCHEMBL2432856 | 0.83 | ITGB1 (0.80) | ITGB1ITGA4 | |
| SCHEMBL1170751 | 0.82 | ITGB1 (0.70) | ITGB1ITGA4MEN1KMT2AKDM1A | |
| Water SCHEMBL2128631 | 0.82 | ITGB1 (0.69) | ITGB1ITGA4MEN1KMT2AKDM1A | |
| Water SCHEMBL1170415 | 0.81 | ITGB1 (0.61) | ITGB1ITGA4MEN1KMT2AKDM1A | |
| Bicarbonate SCHEMBL2438579 | 0.80 | ITGB1 (0.60) | ITGB1ITGA4MEN1KMT2AKDM1A | |
| SCHEMBL2429857 | 0.79 | ITGB1 (0.72) | ITGB1ITGA4MEN1KMT2AKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1346982-B1 | VLA-4 INHIBITORS | DAIICHI SEIYAKU CO (JP) | 2011-09-14 | — | — | EP | disclosed |