Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 9/20 | 0.67 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.63 |
| ▸ | GSK3B | P49841 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | CNR2 | P34972 | 1/20 | 0.54 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2433439 | 0.80 | CASR (1.00) | CASRALDH1A1MAPTLMNACNR1 | |
| SCHEMBL4902252 | 0.80 | EPHX1 (0.73) | EPHX1KDM4EGSK3BALDH1A1MAPT | |
| SCHEMBL12196197 | 0.80 | EPHX1 (1.00) | EPHX1KDM4EGSK3BALDH1A1MAPT | |
| SCHEMBL29971510 | 0.78 | KDM4E (1.00) | EPHX1KDM4EGSK3BALDH1A1MAPT | |
| SCHEMBL1395176 | 0.78 | KDM4E (1.00) | EPHX1KDM4EGSK3BALDH1A1MAPT | |
| SCHEMBL2433522 | 0.78 | CASR (0.67) | CASRMAPTMEN1KMT2ALMNA | |
| SCHEMBL10089308 | 0.77 | EPHX1 (0.83) | EPHX1KDM4EGSK3BALDH1A1MAPT | |
| SCHEMBL20472314 | 0.77 | NPY5R (0.65) | EPHX1KDM4EGSK3BALDH1A1MAPT | |
| SCHEMBL8545918 | 0.77 | EPHX1 (0.64) | EPHX1KDM4EGSK3BALDH1A1MAPT | |
| SCHEMBL31254114 | 0.77 | NPY5R (0.65) | EPHX1KDM4EGSK3BALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2366698-A1 | Derivatives of urea and related diamines, methods for their manufacture, and uses therefor | Galapagos SAS (FR) | 2011-09-21 | — | — | EP | disclosed |
| US-20080125424-A1 | Derivatives of urea and related diamines, methods for their manufacture, and uses therefor | GALAPAGOS SAS (FR) | 2008-05-29 | — | — | US | disclosed |
| US-20080125424-A1 | Derivatives of urea and related diamines, methods for their manufacture, and uses therefor | GALAPAGOS SAS (FR) | 2008-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080125424-A1 | Derivatives of urea and related diamines, methods for their manufacture, and uses therefor | UTS2R, CASR, GPR17 | CASR 2/4885EPHX1 2713/4885KDM4E 3540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.