SCHEMBL24328651

SCHEMBL24328651

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc4c(c3)C(c3ccccc3)(c3ccc5c6ccccc6c6ccccc6c5c3)c3ccccc3-4)n2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.41
KMT2A Q03164 6/20 0.41
MAPT P10636 4/20 0.41
LMNA P02545 3/20 0.41
KDM4E B2RXH2 3/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
OPRK1 P41145 1/20 0.41
ALDH1A1 P00352 3/20 0.36
HPGD P15428 3/20 0.36
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
PDK2 Q15119 5/20 0.35
NTSR1 P30989 1/20 0.33
ATM Q13315 2/20 0.33
GLA P06280 1/20 0.33
POLB P06746 2/20 0.32
MAPK1 P28482 2/20 0.31
TDP1 Q9NUW8 2/20 0.31
ADORA2A P29274 2/20 0.31
ADORA1 P30542 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24169521 0.94 MEN1 (0.39) MEN1KMT2AMAPTLMNAKDM4E
SCHEMBL24169616 0.94 MEN1 (0.39) MEN1KMT2AMAPTLMNAKDM4E
SCHEMBL24328615 0.93 MEN1 (0.40) MEN1KMT2AMAPTLMNAKDM4E
SCHEMBL25557540 0.91 MEN1 (0.37) MEN1KMT2AMAPTLMNAKDM4E
SCHEMBL24041538 0.91 MEN1 (0.46) MEN1KMT2AMAPTLMNAKDM4E
SCHEMBL24328130 0.90 KMT2A (0.39) MEN1KMT2AMAPTLMNAKDM4E
SCHEMBL12133795 0.89 MEN1 (0.46) MEN1KMT2AMAPTLMNAKDM4E
SCHEMBL12133811 0.89 MEN1 (0.46) MEN1KMT2AMAPTLMNAKDM4E
SCHEMBL24328666 0.89 MAPT (0.38) MEN1KMT2AMAPTLMNAKDM4E
SCHEMBL19754708 0.89 PDK2 (0.39) MEN1KMT2AMAPTLMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11299466-B2 Compound, and organic electronic element comprising same LG CHEM, LTD. 2022-04-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11299466-B2 Compound, and organic electronic element comprising same OR10J3, ETV6, ODC1 MEN1 195/4885KMT2A 639/4885MAPT 2593/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.