Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 18/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23680788 | 0.86 | HPGD (1.00) | HPGDALDH1A1NPC1GLARAB9A | |
| SCHEMBL23675337 | 0.85 | HPGD (1.00) | HPGDALDH1A1NPC1GLARAB9A | |
| SCHEMBL31482909 | 0.85 | HPGD (1.00) | HPGDALDH1A1NPC1GLARAB9A | |
| SCHEMBL23675143 | 0.83 | HPGD (0.84) | HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL24463674 | 0.82 | HPGD (1.00) | HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL24463713 | 0.82 | HPGD (0.82) | HPGDALDH1A1NPC1GLARAB9A | |
| SCHEMBL23675179 | 0.80 | HPGD (1.00) | HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL24463679 | 0.80 | HPGD (0.83) | HPGDALDH1A1NPC1GLARAB9A | |
| SCHEMBL23680568 | 0.77 | HPGD (1.00) | HPGDALDH1A1NPC1GLARAB9A | |
| SCHEMBL23675340 | 0.77 | HPGD (1.00) | HPGDALDH1A1NPC1GLARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022082009-A1 | INHALED FORMULATIONS OF PGDH INHIBITORS AND METHODS OF USE THEREOF | EPIRIUM BIO INC. (US) | 2022-04-21 | — | — | WO | disclosed |