Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | KDM2B | Q8NHM5 | 5/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 5/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | SMO | Q99835 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24329023 | 0.83 | HPGD (0.38) | HPGDKDM2BMGLLIRAK4 | |
| SCHEMBL23680753 | 0.82 | HPGD (0.53) | HPGDMGLL | |
| SCHEMBL23680819 | 0.74 | HPGD (0.67) | HPGDMGLL | |
| SCHEMBL24328715 | 0.74 | IRAK4 (0.38) | HPGDMGLLIRAK4 | |
| SCHEMBL24328716 | 0.73 | MAPKAPK2 (0.49) | HPGD | |
| SCHEMBL23680739 | 0.72 | HPGD (0.60) | HPGDMGLL | |
| SCHEMBL24329024 | 0.72 | HPGD (0.36) | HPGDKDM2BMGLLIRAK4 | |
| SCHEMBL24329042 | 0.71 | HPGD (0.52) | HPGDKDM2B | |
| SCHEMBL23680747 | 0.69 | HPGD (0.52) | HPGDMGLL | |
| SCHEMBL23680749 | 0.69 | HPGD (0.53) | HPGDMGLLIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022082009-A1 | INHALED FORMULATIONS OF PGDH INHIBITORS AND METHODS OF USE THEREOF | EPIRIUM BIO INC. (US) | 2022-04-21 | — | — | WO | disclosed |