Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 14/20 | 0.64 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23680802 | 0.85 | HPGD (0.67) | HPGDMGLLADORA2ADPP4PARP1 | |
| SCHEMBL23680744 | 0.85 | HPGD (0.67) | HPGDMGLLADORA2ADPP4PARP1 | |
| SCHEMBL24463693 | 0.85 | HPGD (0.73) | HPGDMGLLADORA2AALDH1A1 | |
| SCHEMBL23680790 | 0.83 | HPGD (0.71) | HPGDMGLLADORA2AALDH1A1KDM4E | |
| SCHEMBL23675323 | 0.83 | HPGD (0.64) | HPGDMGLLADORA2ADPP4ALDH1A1 | |
| SCHEMBL24463733 | 0.82 | HPGD (0.79) | HPGDMGLLADORA2ADPP4ALDH1A1 | |
| SCHEMBL23680748 | 0.82 | HPGD (0.66) | HPGDMGLLADORA2AALDH1A1 | |
| SCHEMBL23680820 | 0.81 | HPGD (0.68) | HPGDMGLLPARP1ALDH1A1 | |
| SCHEMBL23680796 | 0.81 | HPGD (0.68) | HPGDMGLLADORA2AALDH1A1KDM4E | |
| SCHEMBL23675331 | 0.80 | HPGD (0.69) | HPGDMGLLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022082009-A1 | INHALED FORMULATIONS OF PGDH INHIBITORS AND METHODS OF USE THEREOF | EPIRIUM BIO INC. (US) | 2022-04-21 | — | — | WO | disclosed |