Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 20/20 | 0.90 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.72 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.72 |
| ▸ | HTR1A | P08908 | 1/20 | 0.72 |
| ▸ | HTR2A | P28223 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24329466 | 0.95 | GLP1R (1.00) | GLP1RCYP2C8KCNH2HTR1AHTR2A | |
| SCHEMBL25340045 | 0.95 | GLP1R (1.00) | GLP1RCYP2C8KCNH2HTR1AHTR2A | |
| SCHEMBL24329320 | 0.94 | GLP1R (0.88) | GLP1RCYP2C8KCNH2HTR1AHTR2A | |
| SCHEMBL24329324 | 0.94 | GLP1R (0.88) | GLP1RCYP2C8KCNH2HTR1AHTR2A | |
| SCHEMBL28729025 | 0.93 | GLP1R (1.00) | GLP1RCYP2C8KCNH2HTR1AHTR2A | |
| SCHEMBL29555560 | 0.93 | GLP1R (1.00) | GLP1RCYP2C8KCNH2HTR1AHTR2A | |
| SCHEMBL24329248 | 0.93 | GLP1R (1.00) | GLP1RCYP2C8KCNH2HTR1AHTR2A | |
| SCHEMBL24330231 | 0.92 | GLP1R (0.88) | GLP1RCYP2C8KCNH2HTR1AHTR2A | |
| SCHEMBL29555321 | 0.92 | GLP1R (0.88) | GLP1RCYP2C8KCNH2HTR1AHTR2A | |
| SCHEMBL20280085 | 0.90 | GLP1R (0.89) | GLP1RCYP2C8KCNH2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078152-A1 | BENZIMIDAZOLONE GLP-1 RECEPTOR AGONIST AND USE THEREOF | 杭州中美华东制药有限公司 | 2022-04-21 | — | — | WO | disclosed |