SCHEMBL24329504

SCHEMBL24329504

COc1cc(C(=O)O)ccc1COc1cccc(C2CCN(C(=O)OC(C)(C)C)CC2)n1

nearest known ligand 0.52

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GLP1R P43220 20/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29555039 1.00 GLP1R (0.52) GLP1R
SCHEMBL24329283 0.93 GLP1R (0.46) GLP1R
SCHEMBL25338714 0.92 GLP1R (0.50) GLP1R
SCHEMBL29554851 0.92 GLP1R (0.45) GLP1R
SCHEMBL24329558 0.92 GLP1R (0.45) GLP1R
SCHEMBL29556342 0.92 GLP1R (0.46) GLP1R
SCHEMBL29555226 0.92 GLP1R (0.45) GLP1R
SCHEMBL24330465 0.92 GLP1R (0.46) GLP1R
SCHEMBL24329552 0.92 GLP1R (0.45) GLP1R
SCHEMBL25339183 0.90 GLP1R (0.55) GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4227299-A1 BENZIMIDAZOLONE GLP-1 RECEPTOR AGONIST AND USE THEREOF Hangzhou Zhongmeihuadong Pharmaceutical Co., Ltd. (CN) 2023-08-16 EP disclosed
EP-4227299-A1 BENZIMIDAZOLONE GLP-1 RECEPTOR AGONIST AND USE THEREOF Hangzhou Zhongmeihuadong Pharmaceutical Co., Ltd. (CN) 2023-08-16 EP disclosed
CN-116348464-A Benzimidazolone GLP-1 receptor agonists and uses thereof 杭州中美华东制药有限公司 2023-06-27 CN disclosed
WO-2022078152-A1 BENZIMIDAZOLONE GLP-1 RECEPTOR AGONIST AND USE THEREOF 杭州中美华东制药有限公司 2022-04-21 WO disclosed