SCHEMBL24329752

SCHEMBL24329752

BN1CCC(c2cccc(OCc3ccc(Br)cc3F)n2)CC1

nearest known ligand 0.47

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GLP1R P43220 20/20 0.47
KCNH2 Q12809 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25954193 0.87 GLP1R (0.44) GLP1RKCNH2
SCHEMBL30149289 0.85 GLP1R (0.43) GLP1RKCNH2
SCHEMBL30951873 0.85 GLP1R (0.43) GLP1RKCNH2
SCHEMBL24485288 0.85 GLP1R (0.43) GLP1RKCNH2
SCHEMBL25955940 0.84 GLP1R (0.62) GLP1R
SCHEMBL26218378 0.82 GLP1R (0.52) GLP1RKCNH2
SCHEMBL25952433 0.81 GLP1R (0.53) GLP1R
SCHEMBL25959193 0.81 GLP1R (0.60) GLP1R
SCHEMBL24329751 0.81 GLP1R (0.48) GLP1R
SCHEMBL25952495 0.79 GLP1R (0.51) GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022078152-A1 BENZIMIDAZOLONE GLP-1 RECEPTOR AGONIST AND USE THEREOF 杭州中美华东制药有限公司 2022-04-21 WO disclosed