Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.49 |
| ▸ | GLP1R | P43220 | 2/20 | 0.48 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24329751 | 0.90 | GLP1R (0.48) | TRPV3GLP1RDPP4 | |
| SCHEMBL29554988 | 0.86 | GLP1R (0.52) | GLP1R | |
| SCHEMBL30469399 | 0.85 | GLP1R (0.51) | TRPV3GLP1RPRMT5GPR119MAPT | |
| SCHEMBL24329742 | 0.85 | GLP1R (0.46) | TRPV3GLP1RPRMT5GPR119MAPT | |
| SCHEMBL29668702 | 0.84 | GLP1R (0.56) | TRPV3GLP1RSMN1; SMN2 | |
| SCHEMBL29668599 | 0.84 | GLP1R (0.56) | TRPV3GLP1RGPR119MAPTSMN1; SMN2 | |
| SCHEMBL24485767 | 0.84 | GLP1R (0.56) | TRPV3GLP1RSMN1; SMN2 | |
| SCHEMBL24485799 | 0.84 | GLP1R (0.56) | TRPV3GLP1RGPR119MAPTSMN1; SMN2 | |
| SCHEMBL24330297 | 0.84 | GLP1R (0.50) | TRPV3GLP1R | |
| SCHEMBL29555237 | 0.84 | GLP1R (0.50) | TRPV3GLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250263402-A1 | BENZIMIDAZOLONE GLP-1 RECEPTOR AGONIST AND USE THEREOF | HANGZHOU ZHONGMEIHUADONG PHARMACEUTICAL CO., LTD. (CN) | 2025-08-21 | — | — | US | disclosed |
| EP-4227299-A1 | BENZIMIDAZOLONE GLP-1 RECEPTOR AGONIST AND USE THEREOF | Hangzhou Zhongmeihuadong Pharmaceutical Co., Ltd. (CN) | 2023-08-16 | — | — | EP | disclosed |
| EP-4227299-A1 | BENZIMIDAZOLONE GLP-1 RECEPTOR AGONIST AND USE THEREOF | Hangzhou Zhongmeihuadong Pharmaceutical Co., Ltd. (CN) | 2023-08-16 | — | — | EP | disclosed |
| CN-116348464-A | Benzimidazolone GLP-1 receptor agonists and uses thereof | 杭州中美华东制药有限公司 | 2023-06-27 | — | — | CN | disclosed |
| WO-2022078152-A1 | BENZIMIDAZOLONE GLP-1 RECEPTOR AGONIST AND USE THEREOF | 杭州中美华东制药有限公司 | 2022-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250263402-A1 | BENZIMIDAZOLONE GLP-1 RECEPTOR AGONIST AND USE THEREOF | GLP1R, GIPR, GCGR | TRPV3 316/4885GLP1R 1/4885PRMT5 3198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.