Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | PSMB8 | P28062 | 11/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30751823 | 0.78 | PDE3B (0.44) | ADORA2AADORA1POLB | |
| SCHEMBL22530235 | 0.77 | HTT (0.50) | HTTHSD17B10PSMB8KDM4EGAA | |
| SCHEMBL22530441 | 0.77 | HSD17B10 (0.50) | HTTHSD17B10PSMB8KDM4EGAA | |
| SCHEMBL5530565 | 0.72 | KDM4E (0.49) | HTTHSD17B10PSMB8KDM4EGAA | |
| SCHEMBL29255629 | 0.70 | PSMB8 (0.40) | HTTHSD17B10PSMB8KDM4EGAA | |
| SCHEMBL29422383 | 0.67 | HSD17B10 (1.00) | HTTHSD17B10PSMB8KDM4EGAA | |
| SCHEMBL13735810 | 0.65 | KDM4E (0.50) | HTTHSD17B10PSMB8KDM4EGAA | |
| SCHEMBL6975590 | 0.64 | HTT (0.44) | HTTHSD17B10PSMB8KDM4EGAA | |
| SCHEMBL38656287 | 0.64 | — | — | |
| SCHEMBL33524090 | 0.63 | PSMB8 (0.61) | HTTHSD17B10PSMB8KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078971-A1 | NOVEL COMPOUNDS | AC IMMUNE SA (CH) | 2022-04-21 | — | — | WO | disclosed |