Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 11/20 | 1.00 |
| ▸ | FYN | P06241 | 9/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16332279 | 0.93 | DYRK1A (0.87) | DYRK1AFYN | |
| SCHEMBL102421 | 0.90 | DYRK1A (0.91) | DYRK1AFYN | |
| SCHEMBL26745373 | 0.86 | DYRK1A (1.00) | DYRK1AFYN | |
| SCHEMBL24333204 | 0.84 | DYRK1A (1.00) | DYRK1AFYN | |
| SCHEMBL24333076 | 0.83 | DYRK1A (1.00) | DYRK1AFYN | |
| SCHEMBL24333229 | 0.82 | DYRK1A (0.77) | DYRK1AFYN | |
| SCHEMBL18613460 | 0.82 | FYN (1.00) | DYRK1AFYN | |
| SCHEMBL24333230 | 0.82 | DYRK1A (0.83) | DYRK1AFYN | |
| SCHEMBL24333075 | 0.82 | DYRK1A (0.80) | DYRK1AFYN | |
| SCHEMBL26745677 | 0.82 | DYRK1A (0.83) | DYRK1AFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230355617-A1 | SMALL MOLECULE INHIBITORS OF LEMUR TYROSINE KINASE 3 | THE UNIVERSITY OF SUSSEX (GB) | 2023-11-09 | — | — | US | disclosed |
| US-20230355617-A1 | SMALL MOLECULE INHIBITORS OF LEMUR TYROSINE KINASE 3 | THE UNIVERSITY OF SUSSEX (GB) | 2023-11-09 | — | — | US | disclosed |
| WO-2022053838-A1 | SMALL MOLECULE INHIBITORS OF LEMUR TYROSINE KINASE 3 | THE UNIVERSITY OF SUSSEX (GB) | 2022-03-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230355617-A1 | SMALL MOLECULE INHIBITORS OF LEMUR TYROSINE KINASE 3 | LMTK3, LMTK2, LIMK1 | DYRK1A 332/4885FYN 69/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.