SCHEMBL2433459

SCHEMBL2433459

C[C@H]1C[C@@H](OC(F)N2CCCC2)CCC1C(=O)O

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2429488 0.77 TSHR (0.33) TSHR
SCHEMBL2433477 0.71 SMN1; SMN2 (0.42) ALDH1A1TSHR
SCHEMBL2432194 0.71 SMN1; SMN2 (0.42) ALDH1A1TSHR
SCHEMBL2429788 0.71 SMN1; SMN2 (0.42) ALDH1A1TSHR
SCHEMBL6866827 0.70 GABRR1 (0.36)
SCHEMBL17814233 0.69 GABRR1 (0.34)
SCHEMBL17802833 0.69 GABRR1 (0.34)
SCHEMBL17803107 0.69 GABRR1 (0.34)
SCHEMBL2430942 0.66 SMN1; SMN2 (0.35) ALDH1A1
SCHEMBL2869807 0.63 GABRR1 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1346982-B1 VLA-4 INHIBITORS DAIICHI SEIYAKU CO (JP) 2011-09-14 EP disclosed