Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 19/20 | 0.67 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.49 |
| ▸ | NCS1 | P62166 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2429162 | 0.95 | CASR (0.65) | CASRCSNK1DNCS1 | |
| SCHEMBL2432147 | 0.91 | CASR (0.78) | CASR | |
| SCHEMBL2462733 | 0.91 | CASR (0.65) | CASRCSNK1DNCS1 | |
| SCHEMBL125762 | 0.87 | CASR (0.83) | CASR | |
| SCHEMBL2432635 | 0.87 | CASR (0.64) | CASRCSNK1DNCS1 | |
| SCHEMBL2430770 | 0.86 | CASR (0.69) | CASRCSNK1DNCS1 | |
| SCHEMBL2430639 | 0.86 | CASR (0.65) | CASR | |
| SCHEMBL2435305 | 0.86 | CASR (0.75) | CASR | |
| SCHEMBL2463138 | 0.86 | CASR (0.60) | CASRCSNK1DNCS1 | |
| SCHEMBL2429311 | 0.86 | CASR (0.60) | CASRCSNK1DNCS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2366698-A1 | Derivatives of urea and related diamines, methods for their manufacture, and uses therefor | Galapagos SAS (FR) | 2011-09-21 | — | — | EP | disclosed |