SCHEMBL24337408

SCHEMBL24337408

Fc1cc(C#Cc2ccccc2)ccc1N=C=S

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 6/20 0.47
FFAR4 Q5NUL3 5/20 0.47
APP P05067 1/20 0.40
MIF P14174 1/20 0.38
MAPT P10636 1/20 0.37
ABCB11 O95342 1/20 0.36
ALDH1A1 P00352 1/20 0.36
NR3C1 P04150 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
ADRA2A P08913 1/20 0.36
ADORA3 P0DMS8 1/20 0.36
HPGD P15428 1/20 0.36
ALOX15 P16050 1/20 0.36
ADRA2C P18825 1/20 0.36
MAOA P21397 1/20 0.36
DRD1 P21728 1/20 0.36
SLC6A4 P31645 1/20 0.36
HTR2B P41595 1/20 0.36
CCR2 P41597 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24296894 0.88 FFAR1 (0.44) FFAR1FFAR4GRM5HAO1
SCHEMBL19057523 0.85 FFAR1 (0.33) FFAR1FFAR4GRM5
SCHEMBL14015552 0.85 GRM5 (0.36) FFAR1FFAR4ALDH1A1GRM5CA12
SCHEMBL91868 0.83 APP (0.45) APPMIFCA12CA1CA2
SCHEMBL23051752 0.81 APP (0.37) FFAR1FFAR4APP
SCHEMBL17506891 0.81 KCNH2 (0.33) FFAR1FFAR4GRM5CA12CA1
SCHEMBL24184907 0.80 ACACB (0.41) FFAR1FFAR4
SCHEMBL20780041 0.80 NQO1 (0.40) TDP1
SCHEMBL25918967 0.80 APP (0.40) FFAR1FFAR4APPMIFMAPT
SCHEMBL24538431 0.79 FFAR1 (0.44) FFAR1FFAR4APPMIFMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220119710-A1 LIQUID CRYSTAL COMPOSITION AND ELEMENT USED FOR PHASE CONTROL OF ELECTROMAGNETIC WAVE SIGNAL JNC CORPORATION (JP) 2022-04-21 US disclosed