Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 17/20 | 0.58 |
| ▸ | IDH2 | P48735 | 8/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24343844 | 0.89 | IDH1 (0.56) | IDH1IDH2 | |
| SCHEMBL29763461 | 0.84 | IDH1 (0.58) | IDH1IDH2 | |
| SCHEMBL15102497 | 0.84 | IDH1 (0.58) | IDH1IDH2 | |
| SCHEMBL15102486 | 0.81 | IDH1 (0.64) | IDH1IDH2 | |
| SCHEMBL29763470 | 0.81 | IDH1 (0.64) | IDH1IDH2 | |
| SCHEMBL18198794 | 0.81 | IDH1 (0.67) | IDH1IDH2 | |
| SCHEMBL15102480 | 0.78 | IDH1 (0.62) | IDH1IDH2 | |
| SCHEMBL29763348 | 0.78 | IDH1 (0.62) | IDH1IDH2 | |
| SCHEMBL29763354 | 0.77 | IDH1 (0.74) | IDH1IDH2 | |
| SCHEMBL15102454 | 0.77 | IDH1 (0.74) | IDH1IDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3984997-A1 | THERAPEUTICALLY ACTIVE COMPOUNDS AND THEIR METHODS OF USE | Les Laboratoires Servier SAS (FR) | 2022-04-20 | — | — | EP | disclosed |