⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21937639 | 0.78 | — | — | |
| SCHEMBL21341478 | 0.78 | — | — | |
| SCHEMBL21341339 | 0.76 | HMGCR (0.31) | — | |
| SCHEMBL1912979 | 0.70 | CHRNA7 (0.33) | — | |
| SCHEMBL1702135 | 0.69 | HMGCR (0.36) | — | |
| SCHEMBL18532053 | 0.68 | ADORA2A (0.31) | — | |
| SCHEMBL25466578 | 0.66 | — | — | |
| SCHEMBL23767706 | 0.65 | — | — | |
| SCHEMBL279200 | 0.65 | SYK (0.39) | — | |
| SCHEMBL25998007 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230144211-A1 | ANTIFOLATE LINKER-DRUGS AND ANTIBODY-DRUG CONJUGATES | BYONDIS B.V. (NL) | 2023-05-11 | — | — | US | disclosed |
| US-20220119392-A1 | ANTIFOLATE LINKER-DRUGS AND ANTIBODY-DRUG CONJUGATES | BYONDIS B.V. (NL) | 2022-04-21 | — | — | US | disclosed |