Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KDM5A | P29375 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24344030 | 0.74 | — | — | |
| SCHEMBL24344032 | 0.74 | KDM5A (0.32) | KDM5A | |
| SCHEMBL24344359 | 0.73 | TTK (0.30) | — | |
| SCHEMBL19365017 | 0.71 | KDM5A (0.37) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL17802271 | 0.71 | BTK (0.34) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL17802285 | 0.70 | KDM5A (0.36) | KDM4EALDH1A1GAAHPGDKDM5A | |
| SCHEMBL10027232 | 0.70 | KDM5A (0.36) | KDM4EALDH1A1GAAHPGDKDM5A | |
| SCHEMBL24344625 | 0.69 | KDM5A (0.30) | KDM5A | |
| SCHEMBL19361128 | 0.68 | KDM6B (0.33) | ALDH1A1KDM5A | |
| SCHEMBL21577470 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3227292-B1 | 4H-PYRIDO[1,2-a]PYRIMIDIN-4-ONE COMPOUNDS | ALTERITY THERAPEUTICS LTD (AU) | 2022-03-09 | — | — | EP | disclosed |