Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 20/20 | 0.45 |
| ▸ | NTRK3 | Q16288 | 9/20 | 0.45 |
| ▸ | NTRK2 | Q16620 | 9/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22695100 | 1.00 | NTRK1 (0.45) | NTRK1NTRK3NTRK2 | |
| SCHEMBL22688739 | 0.94 | NTRK1 (0.46) | NTRK1NTRK3NTRK2 | |
| SCHEMBL22688740 | 0.94 | NTRK1 (0.46) | NTRK1NTRK3NTRK2 | |
| SCHEMBL22688882 | 0.91 | NTRK1 (0.42) | NTRK1NTRK3NTRK2 | |
| SCHEMBL22688879 | 0.91 | NTRK1 (0.42) | NTRK1NTRK3NTRK2 | |
| SCHEMBL24347465 | 0.88 | NTRK1 (0.47) | NTRK1NTRK3NTRK2 | |
| SCHEMBL24347036 | 0.88 | NTRK1 (0.45) | NTRK1NTRK3NTRK2 | |
| SCHEMBL22688746 | 0.88 | NTRK1 (0.45) | NTRK1NTRK3NTRK2 | |
| SCHEMBL22688743 | 0.88 | NTRK1 (0.45) | NTRK1NTRK3NTRK2 | |
| SCHEMBL29422670 | 0.88 | NTRK1 (0.45) | NTRK1NTRK3NTRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3974434-A1 | MACROLIDE DERIVATIVES, PREPARATION METHOD AND APPLICATION THEREOF | Zhejiang Hisun Pharmaceutical Co., Ltd. (CN) | 2022-03-30 | — | — | EP | disclosed |