SCHEMBL2434764

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2434765	1.00	GRM4 (0.35)	GRM4NR1I2ROCK2PARP1DGAT1
	SCHEMBL1442834	0.95	GRM4 (0.34)	GRM4NR1I2ROCK2PARP1DGAT1
	SCHEMBL1442830	0.95	GRM4 (0.34)	GRM4NR1I2ROCK2PARP1DGAT1
	SCHEMBL2435943	0.92	GRM4 (0.38)	GRM4ROCK2PARP1S1PR1TP53
	SCHEMBL2435948	0.92	GRM4 (0.38)	GRM4ROCK2PARP1S1PR1TP53
	SCHEMBL2430602	0.92	GRM4 (0.33)	GRM4NR1I2ROCK2PARP1DGAT1
	SCHEMBL2430605	0.92	GRM4 (0.33)	GRM4NR1I2ROCK2PARP1DGAT1
	SCHEMBL17244339	0.90	GRM4 (0.33)	GRM4NR1I2ROCK2
	SCHEMBL9933479	0.90	GRM4 (0.33)	GRM4NR1I2ROCK2PARP1
	SCHEMBL2428709	0.87	GRM4 (0.37)	GRM4ROCK2PARP1DGAT1GRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.