SCHEMBL24348120

SCHEMBL24348120

NCCCC[C@H]1C(=O)N[C@@H]2C(=O)N([C@H](CO)CSSCCC(=O)N[C@@H](Cc3ccc(O)cc3)C(=O)NCC(=O)N1c1c[nH]c3ccccc13)[C@H]2O

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ SSTR2 P30874 5/20 0.41
▸ SSTR5 P35346 4/20 0.41
▸ LDLR P01130 13/20 0.37
▸ PCSK9 Q8NBP7 13/20 0.37
▸ ROR1 Q01973 1/20 0.37
▸ ITGB3 P05106 1/20 0.37
▸ ITGAV P06756 1/20 0.37
▸ ITGA2B P08514 1/20 0.37
▸ SSTR3 P32745 2/20 0.37
▸ SSTR4 P31391 3/20 0.36
▸ SSTR1 P30872 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20963294 0.82 SSTR2 (0.52) SSTR2SSTR5LDLRPCSK9SSTR3
SCHEMBL21892339 0.78 SSTR2 (0.56) SSTR2SSTR5SSTR3SSTR4SSTR1
SCHEMBL24348111 0.70 SSTR2 (0.45) SSTR2SSTR5SSTR3SSTR4SSTR1
SCHEMBL20465752 0.66 SSTR2 (0.69) SSTR2SSTR5SSTR3SSTR4SSTR1
SCHEMBL24347585 0.66 SSTR2 (0.36) SSTR2SSTR5LDLRPCSK9SSTR3
SCHEMBL21892055 0.65 SSTR2 (0.70) SSTR2SSTR5SSTR3SSTR4SSTR1
SCHEMBL20465794 0.65 SSTR2 (0.70) SSTR2SSTR5SSTR3SSTR4SSTR1
SCHEMBL18712329 0.65 SSTR2 (0.61) SSTR2SSTR5SSTR3SSTR4SSTR1
SCHEMBL22183489 0.65 SSTR2 (0.69) SSTR2SSTR5SSTR3SSTR4SSTR1
SCHEMBL18712893 0.63 SSTR2 (0.70) SSTR2SSTR5SSTR3SSTR4SSTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220096646-A1 SSTR-TARGETED CONJUGATES AND PARTICLES AND FORMULATIONS THEREOF TVA (ABC), LLC 2022-03-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220096646-A1 SSTR-TARGETED CONJUGATES AND PARTICLES AND FORMULATIONS THEREOF SSTR1, SSTR4, SSTR3 SSTR2 5/4885SSTR5 4/4885LDLR 568/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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