SCHEMBL24348243

SCHEMBL24348243

CCn1nc(C)cc1C(=O)Nc1nc2cc(C(=O)OC)cc(OC)c2n1C/C=C/CN

nearest known ligand 0.74

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
STING1 Q86WV6 19/20 0.74
CYP3A4 P08684 1/20 0.64
IRF3 Q14653 1/20 0.61
ENPP1 P22413 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29080465 1.00 STING1 (0.74) STING1CYP3A4IRF3ENPP1
SCHEMBL29791203 1.00 STING1 (0.74) STING1CYP3A4IRF3ENPP1
SCHEMBL19436569 0.93 STING1 (0.84) STING1CYP3A4ENPP1
SCHEMBL28447140 0.93 STING1 (0.74) STING1CYP3A4ENPP1
SCHEMBL19436571 0.93 STING1 (0.84) STING1CYP3A4ENPP1
Hydrochloric Acid SCHEMBL29686248 0.93 STING1 (0.83) STING1CYP3A4ENPP1
Hydrochloric Acid SCHEMBL21616403 0.93 STING1 (0.83) STING1CYP3A4ENPP1
SCHEMBL26769070 0.92 STING1 (0.69) STING1CYP3A4IRF3ENPP1
SCHEMBL29791288 0.92 STING1 (0.69) STING1CYP3A4IRF3ENPP1
SCHEMBL19451788 0.90 STING1 (0.87) STING1CYP3A4ENPP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023215740-A1 IMMUNOMODULATORY ANTIBODY-DRUG CONJUGATES SEAGEN INC. (US) 2023-11-09 WO disclosed
US-20220119379-A1 IMMUNOMODULATOR HITGEN INC. (CN) 2022-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220119379-A1 IMMUNOMODULATOR STING1, TLR9, CGAS STING1 1/4885CYP3A4 4813/4885IRF3 4/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.