Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | PRKCI | P41743 | 2/20 | 0.31 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21938395 | 0.74 | MAPK1 (0.45) | MAPK1DYRK1APRKCIAXLAKT1 | |
| SCHEMBL2628882 | 0.74 | MAPK1 (0.45) | MAPK1DYRK1APRKCIAXLAKT1 | |
| SCHEMBL30167002 | 0.74 | MAPK1 (0.45) | MAPK1DYRK1APRKCIAXL | |
| SCHEMBL1473269 | 0.74 | DYRK1A (0.53) | MAPK1DYRK1APRKCIAXLAKT1 | |
| SCHEMBL1473042 | 0.74 | MAPK1 (0.45) | MAPK1DYRK1APRKCIAXL | |
| SCHEMBL29691438 | 0.74 | DYRK1A (0.53) | MAPK1DYRK1APRKCIAXLAKT1 | |
| SCHEMBL13524887 | 0.69 | MAPK1 (0.41) | MAPK1DYRK1AAKT1 | |
| SCHEMBL18879031 | 0.69 | MAPK1 (0.45) | MAPK1DYRK1APRKCIAXL | |
| SCHEMBL20712736 | 0.69 | MAPK1 (0.41) | MAPK1DYRK1A | |
| SCHEMBL845394 | 0.69 | MAPK1 (0.41) | MAPK1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022058920-A1 | CASEIN KINASE 1 DELTA MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2022-03-24 | — | — | WO | disclosed |