Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CIT | O14578 | 2/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | CCR8 | P51685 | 1/20 | 0.38 |
| ▸ | CLK2 | P49760 | 2/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | PAK4 | O96013 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | LTK | P29376 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3414600 | 0.79 | PRKCI (0.44) | CITIKBKBCHUKKIT | |
| SCHEMBL26722296 | 0.79 | CIT (0.41) | CITIKBKBCHUKKITAAK1 | |
| SCHEMBL21620452 | 0.77 | CCR1 (0.42) | CCR1CCR5CCR8CLK2DYRK1A | |
| SCHEMBL14294815 | 0.76 | IKBKB (0.36) | CITCCR1CCR5CCR8CLK2 | |
| SCHEMBL855607 | 0.76 | IKBKB (0.48) | CITCCR1CCR5CCR8CLK2 | |
| SCHEMBL16897070 | 0.76 | PIM1 (0.47) | CITCLK2DYRK1ACDK9CDK5 | |
| SCHEMBL21620450 | 0.74 | CCR1 (0.43) | CCR1CCR5CCR8CLK2DYRK1A | |
| SCHEMBL16897077 | 0.73 | CIT (0.39) | CITIKBKBCHUKKIT | |
| SCHEMBL16908324 | 0.73 | CIT (0.42) | CITMAPK8IKBKBCHUKKIT | |
| SCHEMBL17306339 | 0.73 | CCR1 (0.42) | CCR1CCR5CCR8CLK2DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022058920-A1 | CASEIN KINASE 1 DELTA MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2022-03-24 | — | — | WO | disclosed |