SCHEMBL2435231

SCHEMBL2435231

CC(C)(C)OC(=O)N(CC(=O)O)C(=O)CN

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HDAC6 Q9UBN7 2/20 0.37
HDAC1 Q13547 1/20 0.37
HDAC2 Q92769 1/20 0.37
GLRA1 P23415 1/20 0.32
SLC6A9 P48067 1/20 0.32
OR51E2 Q9H255 1/20 0.32
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
GAA P10253 1/20 0.31
KMT2A Q03164 1/20 0.31
NFKB1 P19838 1/20 0.31
NFKB2 Q00653 1/20 0.31
RELA Q04206 1/20 0.31
CA14 Q9ULX7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7719558 0.86 HDAC6 (0.38) HDAC6HDAC1HDAC2KDM4EMEN1
SCHEMBL7248146 0.85 MEN1 (0.38) HDAC6HDAC1HDAC2MEN1GAA
SCHEMBL27606643 0.85 MEN1 (0.31) HDAC6HDAC1HDAC2MEN1GAA
SCHEMBL27505816 0.82 MGAM (0.38) HDAC6HDAC1HDAC2KDM4EGAA
SCHEMBL98566 0.82 GLRA1 (0.47) HDAC6HDAC1HDAC2GLRA1SLC6A9
SCHEMBL3984281 0.81 HDAC6 (0.39) HDAC6HDAC1HDAC2NFKB1NFKB2
Glycine SCHEMBL28774225 0.79 GLRA1 (0.39) HDAC6HDAC1HDAC2GLRA1SLC6A9
SCHEMBL8606993 0.79 HDAC6 (0.38) HDAC6HDAC1HDAC2NFKB1NFKB2
SCHEMBL28195146 0.79 MEN1 (0.33) HDAC6HDAC1HDAC2MEN1GAA
SCHEMBL28195145 0.79 MEN1 (0.33) HDAC6HDAC1HDAC2MEN1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112010943-B To Cu2+Sensitive organic small molecule gel compound and preparation method and application thereof 温州大学 2022-02-15 CN claimed
CN-112010943-A To Cu2+Sensitive organic small molecule gel compound and preparation method and application thereof 温州大学 2020-12-01 CN claimed
US-5130307-A Antibody inhibitors; treating organ graft rejection, fungal infections; antiinflammatory agents AMERICAN HOME PRODUCTS CORPORATION (US) 1992-07-14 US claimed
CN-119219611-B Near infrared fluorescent probe for actively targeting fibroblast growth factor receptor, and preparation method and application thereof 南京诺源医疗器械有限公司 2025-04-18 CN disclosed
CN-119219607-B Near infrared fluorescent probe for actively targeting vascular epidermal growth factor receptor detection and preparation method and application thereof 南京诺源医疗器械有限公司 2025-02-25 CN disclosed
CN-119219607-A Near infrared fluorescent probe for actively targeting vascular epidermal growth factor receptor detection and preparation method and application thereof 南京诺源医疗器械有限公司 2024-12-31 CN disclosed
CN-119219611-A Near infrared fluorescent probe for actively targeting fibroblast growth factor receptor, and preparation method and application thereof 南京诺源医疗器械有限公司 2024-12-31 CN disclosed
CN-119080854-A Cytidine nucleoside compound based on glycine, preparation method and application thereof, and bactericidal and antiviral composition 沈阳农业大学 2024-12-06 CN disclosed
CN-118894839-A Novel FAP inhibitor and application thereof 中国药科大学 2024-11-05 CN disclosed
CN-118496232-A Compound targeting tyrosine protein kinase BTK and application thereof 北京康特莱斯医药科技有限公司 2024-08-16 CN disclosed
CN-112714649-B Cyclic dinucleotide derivatives and antibody drug conjugates thereof 第一三共株式会社 2024-07-02 CN disclosed
US-6034055-A Glycosyl-amides of 2-aminoacylamino-2-deoxy-sugars BAYER AKTIENGESELLSCHAFT (DE) 2000-03-07 US disclosed
US-5905071-A IMMUNE SYSTEM STIMULATORS BAYER AKTIENGESELLSCHAFT (DE) 1999-05-18 US disclosed
CN-1215397-A Acylated N-hydroxymethylthalidomide prodrugs with immunomodulator activity GRUENENTHAL GMBH (DE) 1999-04-28 CN disclosed
EP-0655065-B1 27-HYDROXYRAPAMYCIN AND DERIVATIVES THEREOF AMERICAN HOME PROD (US) 1996-12-11 EP disclosed
US-5302600-A Inducing immunosuppression; antiinflammatory agents, antifungal, antitumor and antiproliferative agents AMERICAN HOME PRODUCTS CORPORATION (US) 1994-04-12 US disclosed
US-5256790-A Antibiotic AMERICAN HOME PRODUCTS CORPORATION (US) 1993-10-26 US disclosed
US-5130307-A Antibody inhibitors; treating organ graft rejection, fungal infections; antiinflammatory agents AMERICAN HOME PRODUCTS CORPORATION (US) 1992-07-14 US disclosed
US-4169141-A 1-Peptidyl derivatives of di-O-aminoglycosyl-1,3-diaminocyclitol antibacterial agents SHERING CORPORATION (US) 1979-09-25 US disclosed
US-4093610-A CYCLIC DODECAPEPTIDE, MULTISTAGE AMERICAN HOME PRODUCTS CORPORATION (US) 1978-06-06 US disclosed