SCHEMBL24354402

SCHEMBL24354402

C=CC(=C)CC/C=C(\C)C[Si](C)(C)Cl

nearest known ligand 0.55

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.55
KMT2A Q03164 1/20 0.32
LSS P48449 4/20 0.32
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24354404 0.78 TSHR (0.50) TSHR
SCHEMBL9580623 0.77 TSHR (0.63) TSHRKMT2ALSSALOX15
SCHEMBL9580560 0.77 TSHR (0.63) TSHRKMT2ALSSALOX15
SCHEMBL7174933 0.75 TSHR (0.65) TSHRKMT2ALSSALOX15
SCHEMBL1301155 0.75 TSHR (0.65) TSHRKMT2AALOX15
SCHEMBL21936846 0.75 TSHR (0.65) TSHRKMT2ALSSALOX15
SCHEMBL10986684 0.75 TSHR (0.65) TSHRKMT2AALOX15
SCHEMBL1301152 0.75 TSHR (0.65) TSHRKMT2AALOX15
SCHEMBL11797432 0.74 TSHR (0.59) TSHRKMT2ALSSALOX15
SCHEMBL11800377 0.74 TSHR (0.59) TSHRKMT2ALSSALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11312843-B2 Bissilylaminosilyl-functionalized conjugated dienes and their use in the production of rubbers SYNTHOS DWORY 7 SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA SPOLKA JAWNA 2022-04-26 US disclosed